BACKGROUND
Clinically uncertain parkinsonian syndromes (CUPS) pose diagnostic challenges, particularly in distinguishing degenerative from non‑degenerative etiologies. DaTscan (123I-ioflupane SPECT) is frequently used to clarify ambiguity, but the magnitude of its diagnostic impact across different initial clinical sus...
J. P. Rissardo, J. Patino, A. F. Fornari Caprara et al.· Journal of clinical neurosci...· 0 citations
The molecular architecture of the SNCA gene is outlined, including regulatory regions, alternative splicing, and untranslated regions that influence αSyn expression and isoform diversity, and seven missense mutations of the SNCA gene are discussed in detail from the genomic level, extending to phenotypic presentations.
Pranaya Gade, Nishant Patel, J. P. Rissardo et al.· Molecular and cellular neuro...· 0 citations
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