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J. P. Thiery

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Review Open access Aug 2026

Epithelial–mesenchymal transition in carcinoma: navigating phenotypic states to target resistance and metastasis

The clinical translation of EMT-directed interventions faces steep methodological hurdles, primarily driven by unverified causal dynamics and unresolved therapeutic safety profiles, and will require dynamic, multi-pronged strategies tailored to specific carcinoma cell states and spatial niches.

Xuecong Wang, C. Zhang, Yi Zhao et al. · 0 citations