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J. Péloponèse

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Open access Aug 2026

A new HIV-1 latency reversing agent activating HIV-Tat

D10 is the first Tat activator available and the first LRA that targets an HIV protein, and induces strong HIV production by latent cell lines and latent cells from people living with HIV-1.

P. Tong, Laetitia Marty, Nawel Chekrit et al. · 0 citations
Jul 2026

Antagonistic regulation of HBZ splicing by hnRNPA1 and hnRNPH1 drives HTLV-1 leukemogenesis

It is established that HBZ inhibits hnRNPA1 transcription, therefore allowing HTLV-1 to hijack host RNA splicing and to generate an oncogenic isoform that drives transformation and chemoresistance and position HBZ splicing and its regulators as therapeutic targets in ATL.

Julie Tram, Célima Mourouvin, Laetitia Marty et al. · 0 citations