This work generated vascularized PIOs (VPIOs) by co-culturing PIOs with blood vessel organoids (BVOs), resulting in integrated structures with BVOs-derived capillary networks that penetrate into the islet structures that enhance β cell maturation and tissue-specific blood vessel specification in vitro and improves graf...
Jing-Qiang Wang, A. Pélissier, Jeffrey S. H. Lin et al.· Cell Stem Cell· 0 citations
Well-characterized iPSC reference panels are critical for developmental and disease-modeling research. We generated eleven iPSC clones from fibroblasts collected from four healthy, unrelated donors (two female, two male) using non-integrating Sendai virus reprogramming. Each clone was extensively validated according to...
Ellen Mosca, E. Stein, Jiss John et al.· Stem Cell Research· 0 citations
High-quality, standardized iPSC reference lines are crucial for disease modeling and regenerative medicine. We generated and extensively characterized thirteen iPSC clones from PBMCs of five healthy donors (three female, two male) using non-integrating Sendai virus. This resource is distinguished by its standardized de...
E. Stein, Ellen Mosca, Jiss John et al.· Stem Cell Research· 0 citations
Four induced pluripotent stem cell lines from peripheral blood mononuclear cells (PBMCs) obtained from members of a family carrying a heterozygous c.184C > T RPS19 mutation exhibiting variable clinical manifestations of Diamond-Blackfan anemia are generated.
Astrid Hagelkruys, E. Stein, Ellen Mosca et al.· Stem Cell Research· 0 citations
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