Author

J. Phelan

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Case report Open access Sep 2026

Whole-genome sequencing guides the successful treatment of extensively drug-resistant TB

low-lying and novel mutations. We recommend incorporating WGS into the national TB diagnostic algorithms for monitoring treatment failures, research, and control programmes to improve outcomes and work toward ending TB. We also recommend strengthening laboratory and administrative systems to prevent diagnostic and admi...

B. Makamure, J. Phelan, T. Bandason et al. · IJTLD open · 0 citations

Open access Aug 2026

Genomic surveillance reveals co-occurrence of Plasmodium falciparum drug resistance variants across diverse transmission settings in Ethiopia

The emergence of antimalarial drug resistance threatens malaria control and elimination efforts in Africa. Ethiopia, once a success story in case reduction, is now experiencing a resurgence. Here we examine key drug resistance genes (Pfmdr1, Pfcrt, Pfk13, Pfdhfr and Pfdhps) and mitochondrial genomes from 605 Plasmodium...

A. Letebo, L. Vanheer, Mengst Engdaw et al. · Nature Microbiology · 0 citations