Author

J. Piñero

3 papers indexed here

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Open access Oct 2026

Capillin, a Polyacetylene from Argyranthemum frutescens, a Promising Hit Compound for Antikinetoplastid Drug Discovery

Chagas disease and leishmaniasis, caused by the protozoan Trypanosoma cruzi and different Leishmania species, respectively, remain public health problems in developing regions due to high prevalence and the limited efficacy and safety of current treatments. Plant-derived natural products are emerging as a promising sou...

Suhib Muhsen Hasan Aldalaeen, Carlos J. Bethencourt-Estrella, I. Sifaoui et al. · Pathogens · 0 citations

Open access Sep 2026

Synthesis of polysubstituted lactones and apoptotic hallmarks in Naegleria fowleri: Exploring their potential as amoebicidal agents.

Naegleria fowleri is the etiological agent of primary amoebic meningoencephalitis, a fulminant infection of the central nervous system that leads to death in most cases. Currently, no standardised therapy is available, and existing treatments are limited by inconsistent efficacy and significant toxicity. β-Hydroxy-γ-la...

Javier Chao-Pellicer, Samuel Delgado-Hernández, S. J. Álvarez-Méndez et al. · Bioorganic chemistry (Print) · 0 citations

Open access Jul 2026

Identifying potential biomarkers for mild COVID-19 in saliva by miRNA profiling using NGS and ddPCR.

The functional analyses revealed that both miRNAs are involved in viral processes and apoptosis regulation, and suggest that miR-374a-5p and miR-590-3p may serve as suitable biomarkers for SARS-CoV-2 infection.

Malena Gajate-Arenas, Candela Sirvent-Blanco, O. García-Pérez et al. · Scientific Reports · 0 citations