J. Plotkin

Prevalence and the rate of antigenic evolution are jointly determined in an eco-evolutionary SIR model

Influenza A persists by continually changing the antigens that its host population recognizes. How fast it evolves and how many hosts it infects are not independent, because the immunity that selects new variants is produced by the infections the pathogen has already caused. We analyze a model of Andreasen et.\ al.\ th...