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Sep 2026

Pharmacological modulation of GLI signaling promotes human iPSC-derived cardiomyocyte maturation via PGC1α-associated mitochondrial programs.

GLI signaling is identified as a modulatory pathway influencing the structural, electrophysiological, and mitochondrial gene programs associated with hiPSC-CM maturation and GLI modulation is highlighted as a strategy to enhance the physiological relevance of hiPSC-derived cardiac models.

M. Shameem, Ahmed Sharara, Ina Xhelilaj et al. · 0 citations
Review Open access Aug 2026

An Immunological and Translational Framework for Interspecies Exogenic Liver Transplantation

This work examines exogenic liver transplantation through an immunology-first, clinical framework with emphasis on early graft injury driven predominantly by innate immune mechanisms at the vascular interface, including complement activation, macrophage mediated clearance, thrombocytopenia, and coagulation dysregulatio...

J. Rao, Anala V. Shetty, Sabarinathan Ramachandran et al. · 0 citations

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