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J. Rayment

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2 papers indexed here

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Open access Sep 2026

Assessing the impact of elexacaftor/tezacaftor/ivacaftor on work productivity and activity impairment in people living with cystic fibrosis in Canada.

BACKGROUND Elexacaftor/tezacaftor/ivacaftor (ETI) has been associated with substantial improvements in lung function and quality of life in people with cystic fibrosis (pwCF). Its longer-term impact on work productivity and daily activity remains less well characterized. METHODS We analyzed data from the CAN-IMPACT-C...

Grace G. Kim, Taryn Wong, J. Rayment et al. · 0 citations
Sep 2026

Safety and efficacy of vanzacaftor-tezacaftor-deutivacaftor in children with cystic fibrosis aged 2-5 years (TIMBERLINE Trial VX21-121-105): a phase 3, open-label study.

BACKGROUND Vanzacaftor-tezacaftor-deutivacaftor was shown to be efficacious and safe in people with cystic fibrosis aged 6 years and older, providing further restoration of CFTR function compared with elexacaftor-tezacaftor-ivacaftor. We aimed to assess the safety and efficacy of vanzacaftor-tezacaftor-deutivacaftor in...

J. Rayment, Gwyneth Davies, J. Gaffin et al. · 1 citation

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