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Author

J. Ribeiro-Silva

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Open access Oct 2026

Otx2 directly regulates tbx3 expression during early eye formation.

Eye field specification requires precise spatiotemporal signaling. Among these signals, the morphogen Noggin blocks both BMP and Activin signaling pathways to generate retinal tissue from pluripotent frog animal cap cells. We previously found that Pax6 and Tbx3 are sufficient to replace Noggin in generating retinal tis...

J. Ribeiro-Silva, Kimberly A. Wong, A. Viczian · 0 citations

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