BACKGROUND
Cutaneous melanoma is rare in Patients of Color (POC), and the genomics are not well understood.
OBJECTIVE
Describe MAPK drivers and tumor mutational burden (TMB) of cutaneous and unknown primary (CUP) melanoma in POC and compare them to non-Hispanic White (NHW) patients.
METHODS
We analyzed a retrospect...
J. Ross, Vanessa R. Weir, Leore Lavin et al.· Journal of American Academy...· 0 citations
PURPOSE
To evaluate the efficacy of ado-trastuzumab emtansine (T-DM1) among patients with advanced/metastatic HER2-amplified solid tumors.
PATIENTS AND METHODS
This was a single-center, non-randomized phase 2 basket trial conducted at Memorial Sloan Kettering Cancer Center. All 95 patients had HER2-amplified metastat...
J. Ross, W. Wong, Lauren Schoech et al.· Clinical Cancer Research· 0 citations
Small-cell lung cancer (SCLC) is an exceptionally aggressive malignancy: highly proliferative, heterogeneous, and frequently metastatic at diagnosis. Although initially responsive to chemotherapy, such responses are typically transient, and recurrent disease has been largely refractory to standard cytotoxics. The past...
J. Ross, K. Hockemeyer, E. Redin et al.· The Lancet· 2 citations
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