This study investigated pH-dependent conformational changes in bovine α-lactalbumin using molecular dynamics simulations of holo and apo forms at pH 3.0, 4.8, and 6.6. Structural integrity was maintained at pH 4.8 and 6.6 (RMSD <3.5 Å), whereas pH 3.0 caused Ca2+ depletion at ∼110 ns, increased flexibility (RMSD ∼5.5 Å...
Thomás Valente de Oliveira, M. D. Polêto, J. S. dos Reis Coimbra et al.· Food Chemistry· 0 citations
Abstract Ion chromatography (IC) is a well-established analytical technique for quantifying ionic species in complex food matrices, offering high sensitivity, selectivity, and multi-analyte detection capability. This review provides a critical and comprehensive overview of IC applications in dairy product quality contr...
Jhonatan Faria da Costa, Moysés Naves de Moraes, Kely de Paula Correa et al.· Brazilian Journal of Food Te...· 0 citations
The rapid expansion of nanotechnology, with over 11,100 products and 100,000 patents, has raised safety concerns for organisms and ecosystems. Nanotoxicology emerged from ultrafine particle studies in the 1990s and was formally established in 2004. This review synthesizes approximately 160 publications and regulatory d...
M. Gonçalves, Igor Jorge Boggione Santos, T. V. de Oliveira et al.· ACS Omega· 0 citations
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