Author

J. Saenz

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Open access Aug 2026

CLEC-1 promotes early IFN response in cDC1s and favors immune dysregulation during sepsis in mice

It is demonstrated that blocking CLEC-1 using an anti-human CLEC-1 monoclonal antibody mitigates hyperinflammation in CLEC-1 humanized mice and suggests its potential as an immunotherapeutic target.

T. Ogor, Esther Porée, J. Saenz et al. · iScience · 0 citations