Author

J. Snijder

2 papers indexed here

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Open access Aug 2026

Reference-free protein sequencing by consensus assembly of redundant de novo peptide reads

Reading a protein’s sequence from tandem mass spectra without a reference is limited by single-spectrum accuracy, most acutely across the hypervariable complementaritydetermining regions of antibodies. Broadly specific proteases tile a protein with long, overlapping peptides, so every residue is covered by many indepen...

Alfred Nilsson, Emil Sporre, Douwe Schulte et al. · bioRxiv · 0 citations

Open access Sep 2026

Integrative structure of norovirus NS3 suggests a role in RNA transport

Human noroviruses (HuNoVs) are the leading global cause of acute gastroenteritis, yet no vaccines or antiviral therapies are currently approved. The non-structural protein NS3 is a membrane-bound AAA+ ATPase of superfamily 3 (SF3) with multiple proposed roles in the norovirus replication cycle. However, the structure...

Meryl Haas, T. Hoeksma, J. Mills et al. · Nature Communications · 0 citations