Objective. Temporal lobe epilepsy (TLE) is associated with disrupted functional integrity in the amygdala-hippocampus complex. Cortico-cortical evoked potentials (CCEPs) can characterize this disruption and have been proposed as biomarkers of the epileptogenic zone (EZ), but their study is typically limited by the spat...
O. Feys, M. Josyula, Nilu Sinha et al.· medRxiv· 0 citations
Structural connectivity partially mediates the seizure-survival association, suggesting preserved network architecture may contribute to why seizure patients survive longer, though the majority of the effect operates through other pathways.
Daniel J. Zhou, M. Jaskir, J. Gal et al.· medRxiv· 0 citations
Cross-sectional findings link cognitive impairment in epilepsy to a reduced capacity for adaptive hub reorganization rather than to pathology alone, and may offer an objective imaging biomarker to complement neuropsychological testing, aid identification of patients at risk for cognitive decline, and inform prognostic...
T. Imtiaz, A. Lucas, E. Zhang et al.· medRxiv· 0 citations
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