Author

J. T. ten Berg

2 papers indexed here

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Open access Aug 2026

Impact of CYP2C19 loss-of-function variants on outcomes in atrial fibrillation patients undergoing percutaneous coronary intervention: rationale and study design of the WOEST-3 genetic substudy

Background: The impact of CYP2C19 loss-of-function (LOF) variants on clopidogrel efficacy in atrial fibrillation (AF) patients undergoing percutaneous coronary intervention (PCI) remains uncertain. While clopidogrel is the preferred P2Y12 inhibitor in combination with oral anticoagulants, approximately one-third of pat...

S. Chiusolo, A. Verburg, C. Morizzo et al. · Bleeding Thrombosis and Vasc... · 0 citations

Open access Aug 2026

Antithrombotic therapy after percutaneous coronary intervention in patients with atrial fibrillation: an individual patient data network meta-analysis.

A patient-level meta-analysis of randomized trials evaluating antithrombotic strategies in patients with AF undergoing PCI found the risk of cardiovascular death, myocardial infarction, or stroke did not significantly differ according to whether patients received a DOAC or VKA, whereas a modest increase in risk with si...

M. Chiarito, R. Mehran, Michael C. Gibson et al. · European Heart Journal · 0 citations