Alzheimer's disease (AD) is a progressive neurodegenerative disease with amyloid-beta (Aβ) plaques, tau tangles, neuroinflammation, and oxidative stress, and it causes cognitive impairment and neuronal loss. The pharmacological treatment is of limited effectiveness, therefore the interest in novel approaches such as in...
Dnyaneshwar S. Shrirame, Amol A. Tatode, Dhiraj Dabhade et al.· Physiology and Behavior· 0 citations
A contextual framework is built that specifies when HO-1 activation is protective versus detrimental, organised around three converging determinants: cell-type specificity, iron-handling capacity, and disease stage, which is extended to the often-overlooked dimensions of sex, age, and model heterogeneity, and used to i...
Tanvi Premchandani, M. Qutub, Tejaswini Thave et al.· Brain Research· 1 citation
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