J. V. G. Takashe

Developmental and transcriptomic alterations in bovine blastocysts derived from oocytes of donors exposed to toxic tall fescue.

Fescue toxicosis, caused by the ingestion of ergot alkaloids present in endophyte-infected tall fescue (E + ), is associated with impaired reproductive performance in beef cattle. Because early embryonic development depends on maternally derived RNAs and proteins accumulated during oocyte maturation, disruption of oocy...