BACKGROUND
This study evaluates DL using GEX and preoperatively available clinical data (PreopClinic) to predict SLNM, and explores their potential for guiding axillary surgery and prognostic assessment.
METHODS
We retrospectively included 6,836 clinically node-negative T1-T2 patients with invasive breast cancer who...
Da-Qu Zhang, J. Staaf, P. Bendahl et al.· Clinical Cancer Research· 0 citations
DNA methylation deregulation is an essential feature of tumor biology, influencing cancer formation and pathogenesis. Analyses of DNA methylation in bulk cancer specimens are challenging due to the high data dimensionality, noise, and mixture of different cell types. Here, we characterized methylation dynamics in cance...
Iñaki Sasiain, D. F. Nacer, M. Jönsson et al.· npj Breast Cancer· 1 citation
It is concluded that high levels of free T3, and a high free T3/T4 ratio were associated with a lower risk of all‐cause mortality and may be a marker of a favourable prognosis.
Annie Brange, Ylva Heyman, Kamil Demircan et al.· Cancer Medicine· 0 citations
Integration of longitudinal clinical data with molecular profiling enabled characterization of real-world treatment patterns, long-term outcomes, molecular subtypes, risk-of-recurrence, and the somatic mutational landscape in this population-based cohort.
L. Saal, H. Dalal, P. Meng et al.· medRxiv· 0 citations
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