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Author

J. Walters

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Open access Aug 2026

Genetic architecture of treatment-resistant schizophrenia across East Asian and European cohorts: insights from GWAS, TWAS, and synaptic pathway analyses

There is promise in pathway-level and multi-omics approaches to elucidate biologically meaningful heterogeneity within SSD and support for synaptic mechanisms as potential targets for understanding and stratifying treatment-resistance is provided.

P. B. Leung, K. C. Wong, S. Smart et al. · 0 citations
Open access Jul 2026

Identifying and Characterising Common Genetic Differences in Schizophrenia and Bipolar Disorder

Case-Case GWAS is used to identify common genetic variants differentially associated with schizophrenia and bipolar disorder, analysing 67,390 schizophrenia cases and 41,917 bipolar disorder cases and demonstrating that genuine divergent genetic effects exist beyond the substantial shared liability.

I. Willcocks, A. Richards, S. Legge et al. · 0 citations

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