Author

J. Ware

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Open access Sep 2026

An Updated Evidence Assessment of the Genetic Causes of Dilated Cardiomyopathy.

BACKGROUND Evidence of the diverse genetic architecture of dilated cardiomyopathy (DCM) continues to emerge and requires reassessment of the clinical relevance of implicated disease genes. Building on the 2019-2020 Clinical Genome Resource evaluation, the DCM gene curation expert panel reconvened in 2024-2025 to conduc...

E. Jordan, Phoenix L. Grover, P. Parker et al. · Circulation · 0 citations

Sep 2026

The molecular landscape of hypertrophic cardiomyopathy across disease stages and genotypes.

Hypertrophic cardiomyopathy (HCM) is marked by asymmetric cardiac wall thickening, hypercontractility, diastolic dysfunction, and fibrosis. Pathogenic sarcomere gene variants cause HCM, but comparable abnormalities occur in patients with unexplained disease, albeit with fewer adverse events. To investigate stage- and g...

E. Adami, Yuri Kim, Sean L. Zheng et al. · Science Translational Medici... · 1 citation