Author

J. Warrick

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Review Oct 2026

Translational research models for variant subtype bladder cancers: A comprehensive review of the current landscape.

Bladder cancer remains a leading cause of cancer-related mortality in the United States, with most cases classified as conventional urothelial carcinoma. However, a substantial subset of patients presents with aggressive variant histologies, including sarcomatoid, plasmacytoid, and micropapillary subtypes. These varian...

Gabriella U. Nanjo, Zi-Rui Fu, S. Smani et al. · Urologic oncology · 0 citations

Open access Oct 2026

Epithelial to mesenchymal transition and M2 macrophages drive aggressiveness in murine and human sarcomatoid urothelial carcinoma

Patients with majority variant subtype histology including sarcomatoid urothelial carcinoma (SUC) have poor outcomes and limited treatment options, and there are few preclinical resources to investigate rare histologic subtypes. We developed three novel variant subtype histology bladder cancer (BC) cell lines by findin...

Yujiro Hayashi, Roy Elias, Eugene F. Douglass et al. · bioRxiv · 0 citations

Review Aug 2026

Mirror Worlds: The Shared Regulatory Architecture of Cell Fate in Development and Cancer.

How emerging single-cell and spatial multi-omics technologies, integrated with artificial intelligence-based modeling, enable mapping of cell state landscapes and transitional trajectories, transforming lineage plasticity from a descriptive phenomenon into a measurable and predictable property of tumor evolution is dis...

Melanie Fraidenburg, Long-Jun Li, R. Kwon et al. · Cancer Letters · 0 citations