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J. Widomska

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Review Open access Oct 2026

Regulation and preservation: dual roles of cholesterol in biological membranes.

Cholesterol modulates key physicochemical properties of lipid bilayers, including phase behavior, lateral organization, acyl-chain order, and permeability to small solutes. In most phospholipid bilayers, cholesterol can be accommodated in a single liquid-ordered phase up to ~50 mol%; above this saturation limit, excess...

W. Subczynski, M. Pasenkiewicz-Gierula, J. Widomska · 0 citations

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