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J. Yesselman

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Open access Aug 2026

Single-base substitutions switch RNA tertiary allostery between positive and negative coupling

A minimal 3D-structure ligand-inducible switch built with a previously designed nanostructure containing an ATP-aptamer and a tetraloop/tetraloop receptor (TL/TLR) tertiary contact provides a platform both as a model for tertiary switching in other large RNA machines and as a foundation for designing synthetic control...

Alabi Oladeji, Brandon G Kircher, J. Yesselman · 0 citations

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