Therapeutic effects of miR-495-3p inhibition and exercise in a transient middle cerebral artery occlusion rat model.
Ischemic stroke is a leading cause of neurological disability, with limited therapeutic options beyond thrombolysis and thrombectomy. This study investigated whether combined exercise training and miR-495-3p inhibitor (miR-495-3p-I) treatment could attenuate endoplasmic reticulum (ER) stress-associated autophagy, reduc...