Astragalus polysaccharides alleviate burn sepsis induced lung injury by suppressing the WTAP/m⁶A/PFKFB3 axis to reduce endothelial pyroptosis
Burn sepsis is a life-threatening complication of severe burns, characterized by pulmonary endothelial injury driving acute lung injury (ALI). Pyroptosis and vascular barrier dysfunction are key pathological in this process; however, their underlying mechanisms remain unclear. Astragalus polysaccharides (APS), a...