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Author

Ja-Lok Ku

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Open access Oct 2026

Integrative characterization of human hepatocellular carcinoma‐derived organoids and their HBV‐associated biology

Abstract Background Hepatocellular carcinoma (HCC) is one of the most aggressive malignancies and is characterized by a high degree of heterogeneity. However, HCC treatment remains difficult, highlighting the need to better define molecular subgroups of HCC and understand their potential relationships with therapeutic...

Seo-Hyeon Kim, YoungRok Choi, Eun-Woo Choi et al. · 0 citations
Open access Jan 2026

Identification of Novel Pathogenic Variants in Familial Adenomatous Polyposis Through Whole Genome Sequencing

It is demonstrated that cryptic pathogenic APC variants beyond the detection limits of routine genetic testing can be resolved through WGS combined with transcript‐level validation, highlighting the importance of transcript‐aware variant interpretation and supports the integration of genome‐wide sequencing and RNA‐base...

Sung-Ryung Choi, Min Jung Kim, Ja-Lok Ku et al. · 0 citations

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