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Author

Jacques Planas

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2 papers indexed here

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Open access Oct 2026

Talazoparib plus enzalutamide in high-volume metastatic hormone-naive prostate cancer: a randomized phase 2 trial.

Combining inhibition of poly(ADP-ribose) polymerase and androgen receptor (AR) pathway has demonstrated clinical activity in men with metastatic prostate cancer, although the extent of benefit in tumors lacking homologous recombination repair (HRR) gene alterations remains uncertain. We conducted a randomized phase 2 t...

F. Zacchi, Elena Castro, Kathleen Imbach et al. · 0 citations
Open access Oct 2026

Gleason Pattern 4 Burden and Adverse Pathology in ISUP Grade Group 2 Prostate Cancer: Implications for Active Surveillance Selection

Simple Summary Selecting men with ISUP Grade Group (GG) 2 prostate cancer for active surveillance remains challenging. In this Flow, 10% (and up to 15% in selected cases) combined with low PSA density reliably identifies organ-confined, non-upgraded pathology. These quantitative thresholds provide objective criteria to...

L. Regis, Clara Perez, Jacques Planas et al. · 0 citations

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