Didecyldimethylammonium chloride (DDAC) is a broad-spectrum quaternary ammonium compound (QAC) extensively utilized as a disinfectant and biocide. Widespread use of DDAC, significantly amplified during COVID-19 pandemic, increased human and environmental exposures, indicating need for updated, quantitative risk assessm...
Eun Ah Lee, Jae Hyeon Park, S. Kwack et al.· Journal of Toxicology and En...· 0 citations
Findings indicate that PKM2 overexpression plays a central role in cisplatin resistance in ovarian cancer, and targeting PKM2 with inhibitors such as shikonin or compound 3K may represent a promising strategy to overcome chemoresistance and improve therapeutic outcomes in patients with advanced ovarian cancer.
Hae-Eun Park, Haeun Lee, Ju Ri Kim et al.· International Journal of Mol...· 0 citations
It is demonstrated that HDAC6 inhibition exerts potent renoprotective effects and represents a promising therapeutic strategy for diabetic nephropathy.
U. Kim, EunAh Lee, Ju Ri Kim et al.· Biochemical Pharmacology· 0 citations
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