Jaime Cardoso-Ortiz

The kynurenine pathway in RNA virus infection: immunometabolic control of antiviral defense and viral persistence

RNA virus infections are shaped by the interplay among viral replication, innate immune sensing, and host metabolism, which together determine the magnitude, duration, and quality of antiviral responses. The tryptophan–kynurenine (Trp–Kyn) pathway has emerged as an important immunometabolic axis linking interferon-driv...