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Author

Jake Dearborn

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Open access Jul 2026

Exportin-5 Links miRNA Biogenesis to the Preservation of B Cell Receptor Surface Expression 2310271

Analysis revealed XPO5 depletion led to increased mutation rates specifically within the BCR light chain, implicating XPO5 in regulating the rate and fidelity of somatic hypermutation (SHM), highlighting a novel link between miRNA nuclear export machinery and the preservation of BCR integrity.

Tylar Kirch, Zachary D. Miller, Jake Dearborn et al. · 0 citations

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