Author

James E. Hudson

h-index 2 View on Semantic Scholar

We have 2 of 6 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Aug 2026

Novel Wnt potentiators induce iPSC-derived cardiomyocyte proliferation and increase embryonic zebrafish heart size.

Canonical Wnt/β-catenin pathway activation can promote cardiomyocyte (CM) cell cycle activity, but translation is limited by off-target and functional liabilities associated with global pathway activation. We identified two small molecules, LRN9 and DF6, which potentiate Wnt/β-catenin signaling through a non-GSK3β mech...

Daniela T Asenjo, Lynn A. C. Devilée, Aaron H. Wasserman et al. · Journal of Molecular and Cel... · 0 citations

Open access Aug 2026

Alpha protein kinase 3 gene therapy restores heart function in mouse and human models of cardiomyopathy

It is demonstrated that adeno-associated virus-mediated delivery of full-length human ALPK3 prevents cardiomyopathy in neonatal mouse models and reverses established disease in adult mice, restoring cardiac structure, function and proteostasis, as well as contractile function in human cardiac organoids carrying ALPK3-...

James W. McNamara, Ellen B. Keen, Rebecca Sutton et al. · Nature Cardiovascular Resear... · 2 citations