James Francis Kwan

Development and characterization of ultrasound-activated polymeric microdroplets for targeted chemotherapy.

Potent antineoplastic agents such as afatinib and freebase doxorubicin exhibit promising antitumor activity but are limited by systemic toxicity, poor aqueous solubility, and restricted delivery to brain tumors. Here, we developed a co-evaporation synthesis strategy that extends a previously validated ultrasound-respon...