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James E. Carpenter

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Open access Sep 2026

Ursodeoxycholic Acid and Parkinson's Disease Risk: An Emulated Target Trial in UK Electronic Health Records.

BACKGROUND Ursodeoxycholic acid (UDCA) has shown mitochondrial and neuroprotective effects and has been proposed as a treatment for Parkinson's disease (PD). However, population-level evidence on its effect on PD risk is lacking. OBJECTIVES To compare the risk of incident PD among UDCA initiators versus matched non-i...

C. Ju, A. Schrag, Camille B. Carroll et al. · 0 citations
Open access Jul 2026

A comparison of missing data approaches for linear regression with missing not at random outcome and predictors

This paper compares several approaches for handling MNAR data in linear regression when missingness depends on both partially observed outcomes and predictors and concludes that not-at-random fully conditional specification was straightforward to implement and yielded coverage close to the nominal level in most scenari...

T. Gorbach, Tim P. Morris, James E. Carpenter · 0 citations

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