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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Jamie H. Docherty

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Review Open access Sep 2026

On-DNA photochemical methods for expanding DNA-encoded library (DEL) chemical space

DNA-encoded libraries (DELs) have become a mainstay of small-molecule discovery, enabling millions to billions of compounds to be screened in a single pooled affinity selection in which each small molecule is covalently linked to a unique DNA identifier. However, the chemistry available for their construction remains l...

Oliver J. Corrigan, Sarah L. Allinson, Jamie H. Docherty · 0 citations

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