Open access
Sep 2026
Design, synthesis, and computational assessment of bis‑oxadiazole ligands targeting α-amylase and α-glucosidase: DFT, docking, and ADME studies.
The combined experimental and computational results demonstrate significant structure-activity relationships within the bis-oxadiazole scaffold, identifying compound 10 as a promising lead candidate for further optimization as a dual enzyme inhibitor for diabetes management.
Shoaib Khan, Tayyiaba Iqbal, B. N. Murtaza et al.
· Future Medicinal Chemistry · 0 citations