Jan H. Christensen

Non-target screening using fast comprehensive two-dimensional liquid chromatography-high-resolution mass spectrometry II: the mosaic workflow - development of a scalable and open-source non-target screening data processing workflow for LC×LC-HRMS and its application to wastewater effluent.

Comprehensive two-dimensional liquid chromatography-high-resolution mass spectrometry (LC × LC-HRMS) offers improved group-type separation and mass spectral quality than one-dimensional LC-HRMS, but its widespread adaption remains limited, partly, due to labor-intensive and non-scalable data-processing workflows. Here,...