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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

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Jan-Martin Daniel

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Open access Oct 2026

Engineering a production platform for the potent antipseudomonal antibiotic mureidomycin A by reprogramming the pacidamycin biosynthetic gene cluster

Uridyl peptide antibiotics display potent activity against Pseudomonas aeruginosa, a pathogen causing severe nosocomial infections. The four subclasses—mureidomycins, pacidamycins, napsamycins, and sansanmycins—inhibit the underexplored bacterial target phospho-MurNAc-pentapeptide translocase (MraY). Structurally, thes...

Panagiota-Hanna Koutsandrea, Richard Sonnengrün, Nils Hauck et al. · 0 citations

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