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Open access Oct 2026

Activation pathway of the human voltage-gated proton channel

This work determines the activation pathway of hHV1, together with structural models of its resting and activated states, using an approach that integrates all-atom continuous constant-pH MD (CpHMD), weighted-ensemble (THE AUTHORS) path sampling, and AlphaFold modeling.

Ming-Zhe Shen, Daniel Kortzak, Christophe Jardin et al. · 0 citations

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