Design, Synthesis, and Cytotoxic Bioevaluations of Some Benzylidene Cinnamoylhydrazides
Three series of benzylidene cinnamoylhydrazides (21 compounds) were synthesized and evaluated for cytotoxic activity against malignant and non-malignant cell lines. Among the compounds tested, 2d and 3c were the most active against Jurkat and CEM leukemia cells, with CC50 values in the low micromolar range. Both compou...