Jul 2026
Implantable 5-FU@ZIF-8 core-shell nanofiber fabricated via emulsion electrospinning: a pH-responsive strategy for localized chemotherapy.
In vivo antitumor studies in CT-26 tumor-bearing mice showed a marked reduction in relative tumor volume and a tumor inhibition rate (TIR) of 70.57%, with stable body weight and no histopathological abnormalities in liver and kidney tissues (H&E), indicating minimal systemic toxicity.
Jasmin Kharazmi-Khorassani, Ahmad Asoodeh, Fatemeh Koohzad
· International journal of pha... · 0 citations