This study used single-cell RNA sequencing to provide a high-resolution characterization of CD4−CD8− γδ T cells in peripheral blood across healthy Mtb-(non-)sensitized and TB disease pre-/post-treatment cohorts and found an activated and cytotoxic gene signature in γδ T cells of TB disease compared with both healthy co...
Kendall Kearns, R. Tippalagama, Ashu Chawla et al.· iScience· 0 citations
The HIPC Project and the ImmuneSpace platform demonstrate the feasibility and benefits of a structured approach to representing human immunological studies to elucidate system-level phenomena.
Kerstin Westendorf, M. Kojima, James A. Overton et al.· Journal of Immunology· 0 citations
Pre-existing antigen-specific antibody titers and baseline monocyte frequencies are identified as the most consistent predictors of post-vaccination immunity, highlighting the dominant role of individual immune setpoints.
Pramod Shinde, Lisa Willemsen, Jiyeun Lee et al.· bioRxiv· 0 citations
Direct evidence is provided that a single ubiquitous mutation-derived neoantigen can generate systemic T-cell responses and clonotype expansion across multiple metastatic sites in a TMB-low, TIL-low tumor.
J. Tanis, Katy J. McCann, F. E. Castañeda-Castro et al.· bioRxiv· 0 citations
CEDAR’s current capabilities, report on progress in curation, database development, and tool availability, and outline the opportunities and challenges ahead for expanding its scope and utility to the cancer research community are described.
Zeynep Koşaloğlu-Yalçın, Ibel Carri, Daniel Marrama et al.· Frontiers in Oncology· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
