Integrated Transcriptomic Analysis of Human Neural Progenitor Cells Reveals Key Pathways and Therapeutic Targets in Fragile X Syndrome
It is shown that the structural and network deficits of FXS are genetically associated at the progenitor state due to altered epigenetic chromatin regulation, histone accumulation, and early synaptic targeting failure, demonstrating that the structural and network deficits of FXS are genetically associated at the proge...