Author

Jeff Errington

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Open access Sep 2026

Utahmycin C, a new glycosylated derivative of a rare azaanthraquinone produced by Streptomyces sp. YD248

Chemical investigation of Streptomyces sp. YD248 led to the isolation of utahmycin C (1), a new glycosylated member of the rare bacterial 1,3-dimethyl-2-azaanthraquinone family. Its structure was established by NMR spectroscopy and high-resolution mass spectrometry, revealing a β-D-glucuronic acid substituent attached...

F. Tajabadi, Andrew M. Piggott, Jeff Errington et al. · Frontiers in Microbiology · 0 citations

Open access Jul 2026

Genetic dissection of persiathiacin biosynthesis defines hierarchical P450 oxidations and reveals a more potent antitubercular intermediate

The results define the enzymatic logic and temporal organization of persiathiacin biosynthesis, providing a conceptual framework for rational diversification of complex thiopeptide natural products.

F. A. Sumang, Maxwell T. Stevens, W. Britton et al. · bioRxiv · 0 citations