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Jefferey H. Price

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Open access Sep 2026

A Human iPSC-Derived Tri-Culture Model of NeuroHIV: HIV Infection, Antiretroviral Drug Effects, Microglial Morphology, and Neuronal Calcium Dynamics

HIV-associated neurocognitive disorders (HAND) can persist despite effective ART and are associated with persistent central nervous system (CNS) viral reservoirs in microglia, chronic neuroinflammation, synaptic dysfunction, and neuronal injury. Thus, human-relevant multicellular CNS models are needed to elucidate neur...

Kara L. Gordon, Christine G. Rines, L. Oja et al. · 0 citations

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