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Author

Jeffery A. Noble

2 papers indexed here

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Open access Aug 2026

The Qβ bacteriophage nanoparticle contributes to the adjuvanticity of antiglycan vaccines through a unique inflammatory pathway.

Current glycoconjugate vaccines often fail to induce durable B cell memory or to provide sufficiently high-affinity antibodies limiting their utility for prophylactic protection against most bacterial and fungal pathogens. We address this limitation by engineering a chemically functionalized protein nanoparticle vaccin...

Kenna Nagy, Jeffery A. Noble, S. Deng et al. · 0 citations
Open access Aug 2026

Immunization with the Tc85-Derived Peptide Displayed on Virus-like Particles Confers Protection against Trypanosoma cruzi Infection

Chagas disease, caused by the Trypanosoma cruzi, remains a major global health burden with limited prophylactic options. We describe a vaccine platform that leverages a peptide epitope derived from the T. cruzi trans-sialidase group II (Tc85pep), displayed on the virus-like particle derived from the PP7 bacteriophage,...

Ugochukwu Oduwe, Giorgi Kenkebashvili, Syed Uddin et al. · 0 citations

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