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Author

Jeffrey L. Bennett

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Open access Aug 2026

Microglia drive demyelination via multiple sclerosis antibodies and BTK signaling

Inhibition of Bruton’s tyrosine kinase (BTK) limited microglial transcriptional changes and prevented myelin loss following microglial envelopment and support BTK inhibition as a therapeutic strategy to prevent demyelination by modulating microglia behavior.

Lindsay A. Osso, Helena J. Barr, Michael E. Stockton et al. · 0 citations

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