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Author

Jeffrey R. Singer

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2 papers indexed here

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Open access Sep 2026

The iron-binding siderophore enterobactin is required for the response of multi-drug resistant Klebsiella pneumoniae to zinc limitation

To persist during infection Klebsiella pneumoniae must overcome nutrient iron and zinc limitation imposed by the host immune system through a process called nutritional immunity. Secreted small molecule siderophores are a major virulence determinant of Klebsiella pneumoniae pathogenesis and are presumed to overcome nut...

Jeffrey R. Singer, D. A. Doyle, D. Kunkle et al. · 0 citations
Open access Sep 2026

Barrier immune memory is programmed by intestinal epithelial cell presentation of cytosol-delivered bacterial antigens

Antigen compartmentalization is known to influence CD4 and CD8 T cell recognition but its impact on immune responses to different antigens expressed by the same pathogen is poorly understood. By tracking the clonal CD4 T cell response to a single epitope shuttled between different virulence proteins of Citrobacter rode...

C. Wilson, M. P. Acharya, Laura Karsch et al. · 1 citation

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