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Jeffry Adiwidjaja

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Open access Sep 2026

Understanding Pharmacokinetic Variability of Pomalidomide: A Physiologically Based Pharmacokinetic Analysis of Disease-Related Physiology, Ethnicity, Hepatic Impairment, Food Effects, Drug Interactions, and Smoking.

BACKGROUND AND OBJECTIVE Understanding interindividual pharmacokinetic variability and potential for drug interactions is of clinical importance for pomalidomide given its long-term use in patients with relapsed and/or refractory multiple myeloma (RRMM). This study aimed to develop a physiologically based pharmacokinet...

Jeffry Adiwidjaja, A. Boddy, Andrew J. McLachlan · 0 citations

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