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Review Open access Sep 2026

Mechanisms of Brain Aging and Their Links to Alzheimer’s and Parkinson’s Disease Pathology

Brain aging is a major risk factor for neurodegenerative disorders and is associated with a progressive loss of neuronal homeostasis. Rather than resulting from a single pathological event, brain aging involves coordinated changes across multiple biological processes, including neuroinflammation, proteostasis impairmen...

Hai-Yi Yi, Hai-Meng Qin, J. Goon et al. · 0 citations
Jul 2026

UHPLC-MS/MS and GC-MS screening of Synedrella nodiflora (L.) Gaertn. and its remedial effect in carbon tetrachloride (CCl4)-induced HepG2 cells against oxidative stress and apoptosis.

ETHNOPHARMACOLOGICAL RELEVANCE Synedrella nodiflora (L.) Gaertn. is known for its medicinal properties in Malaysian traditional practice. Our previous study reported the prophylactic effect of S. nodiflora in protecting carbon tetrachloride (CCl4)-induced hepatic injury in rats. This study aimed to identify the potenti...

Charles Gnanaraj, Wing-Hin Lee, Ching-Yee Loo et al. · 0 citations

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